Aromatic Amino Acid Decarboxylase (AADC) deficiency is an extremely rare disease. So far, only 50 children worldwide have been identified with the disease. It has proved fatal for at least 3 of them. The AADC Research Trust is a children's charity dedicated to funding research, supporting affected families and promoting worldwide disease awareness.

A-CET is a small dynamic UK charity supporting vulnerable African orphans and disabled children through educational scholarships and targeted community led school projects. Overseas it works through local charities run by its ex-students. A-CET has minimal overheads and is run by dedicated experienced professional volunteers.

ABC Trust is a fundraising organisation that supports community projects for street children in some of Brazil's poorest areas. Its aim is to provide the children with the means to make their own future better by offering them a broader horizon and teaching them new skills.

Action for Children in Conflict (AfCiC) works to assist and transform the lives of children affected by various forms of conflict or crisis be it war, extreme poverty, hunger, illness, persecution, or neglect. Our projects focus on helping some of the most disadvantaged, disenfranchised and socially excluded children and young people in Africa. The children we work with come from backgrounds of abject poverty, family breakdown and abuse – both verbal and physical. They are in conflict with the law, living and working in the streets and have little or no access to formal education. Many resort to substance abuse as a means of escaping the cold and hunger which pervade their daily lives. We believe that these children and young people have the capacity to change their own lives for the better, and it is our role to nurture this process. AfCiC works alongside the children and young people, helping to transform them into responsible individuals and productive members of their community, and empowering them to make positive decisions about their futures.

Action for Street Kids is a small UK-based charity which works with local partner organisations in the UK and across the developing world to assist street children, homeless young people, and children affected by chronic poverty and violent conflict.

The Afghan Reading Project (ARP) raises funds for books and educational resources for children and teachers in Afghanistan. With your help, ARP aims to support literacy, a love of reading and education - hope for a better future.

Africa Foundation works with local organisations (NGO's) in Africa to ensure that children have access to their basic necessities. We achieve this through sustainable development projects. It works with locally established homes and schools, for street and orphaned children of Uganda, on sustainable development projects that fit well in their community. These projects fund the provision of food, water and health care for the children. They also provide vocational training skills in farming and crafts and empower the staff and children with a feeling of independence.

Africa Link seeks to do two things To raise awareness of the issues facing those people in Africa who have to deal with extreme poverty on a daily basis. 2. To provide resources to those people to enable them to break out of the vicious cycle of poverty.

The organisations aim is to enable every African Child to receive primary education. The single greatest deterent is hunger and family poverty, our first campaign to combat this is 'the Porridge Club' where we offer a free breakfast of porridge at school before the school day commences.

Africa's Future is a UK organisation set up to fund sustainable development projects in Africa, and in particular projects that seek to provide education for impoverished children. Currently it supports the continuing development and day-to-day running of the Lady Heike Nursery Akatektya, near Cape Coast in Ghana. As the team are all volunteers, the charity has very low running costs which means that all donations go directly to the project in Ghana.

AFRINSPIRE supports indigenous African initiatives in community development and poverty reduction. Engaging in children’s education, women's literacy, transferring technology, and income generation, AFRINSPIRE supports local community development initiatives at their own pace. People and projects are supported in Uganda, Rwanda, Zambia, Ethiopia, Tanzania, and Sudan.

Article 25 of the Universal Declaration of Human Rights is the only article referring to the built environment. It provides that shelter and adequate housing are a human right. article[25] works to build better wherever there is disaster, poverty or need.

Asha-Nepal is a human rights organisation working for women and girls in Nepal. It supports projects to help those from abusive and exploitative situations such as trafficking into the sex industry and domestic labour. Its aim is to empower females through education, training and security, giving them a voice.

Be More is a UK charity that supports grass root development and HIV/AIDS relief organizations in Africa by providing funding and volunteers. These organizations include orphanages, medical clinics, hospices and child rescue centres. You can volunteer at one of our partner organizations in South Africa or make a donation to support their work.

The BEARR Trust works with partners to support health and social welfare, with a view to strengthening civil society, in Russia and Eurasia.

A childrens' home in Tanzania, East Africa - caring for orphaned , abandoned or abused children who have no one else to care for them. To provide them with loving care, education and moral values which will equip and enable them to make a positive improvement and have a lasting impact on the fabric of Tanzanian society and culture when they leave.

The Breakfast Club is based in Southern Tanzania and is committed to combating hunger amongst school children through the development of sustainable school meal programmes in schools. It currently works in partnership with several rural schools providing porridge and fruit to hundreds of pupils.

The Cambodian Futures Foundation (CFF) helps disadvantaged children and orphans in Cambodia by providing financial aid towards everyday expenses such as food, clothing, education and rent.

Educating girls and women is widely recognised as the single most powerful weapon in the fight against poverty and HIV/AIDS in Africa. Since 1993, the Campaign for Female Education (CAMFED) has been supporting girls through school in some of the poorest rural areas of Zimbabwe, Zambia, Ghana and Tanzania. In 2005, more than 246,000 children benefited from CAMFED's programme of educational support, helping them to leave behind a life of poverty.

Casa Reom Trust is a UK based charity co-ordinating fundraising to build a new centre and school for street children near Beira, the second largest city in Mozambique, Africa. Dormitories, classrooms, sanitary blocks, kitchen and communal meeting area are all planned for construction which commenced in 2005.

Transparent giving for deprived children. Direct. Secular. Zero admin costs. Supporting tsunami orphans and dalits in India. Extending to Kenya one day.

Charlotte Wilson was killed in Burundi in December 2000. She had been working as a school teacher in neighbouring Rwanda. The Charlotte Wilson Memorial Fund was established by Charlotte’s family and friends and supports projects in Rwanda and Burundi, focussing on three key areas: Education, Health and Peace building.

Since 1989 ChildHope UK has worked with girls and boys who are vulnerable to violence and injustice. These children are typically living on, or at risk of coming to the streets, abused or exploited, forced into hazardous work, orphaned, or lacking access to education and medical care. Today, ChildHope works in partnership with civil society organisations in Africa, Asia and South America, tackling the causes and consequences of violence against boys and girls. Together, we are working to: " Reduce child abuse and exploitation " Improve child justice and participation " Promote the rights of children affected by HIV and AIDS

Children in Crisis exists to improve the lives of children around the world affected by conflict, deprivation, poverty or other hidden crises, by working in partnership with local communities to provide education, health and protection.

Children in Crossfire exists to make a significant and lasting contribution towards the eradication of poverty. We do this not alone, but by working in a vibrant web of collaborating agencies, each of us contributing something valuable and unique towards our shared vision for a better world.

The Children of China Foundation provides help to orphanages in China to improve the physical and emotional care and welfare of China's abandoned children.

The children of Swaziland is a UK registered charity whose aims are to provide support to the women and children in Swaziland who are infected and affected by HIV/AIDS.

The Christina Noble Children's Foundation is dedicated to serving children in need of emergency and long-term medical care, nutritional rehabilitation, educational opportunities, job placement and protecting those at risk of economic and sexual exploitation. The Foundation seeks to maximise the potential of each child.

Disease and illiteracy keep the poor poor. CINI UK (Child In Need Institute) works to break the cycle of poverty, malnutrition and ill health in India and give children born into poor families the best possible start in life.

Cocoa 's mission is to improve the conditions for babies and children in China's orphanages, by enhancing their quality of care and providing equipment, medicine and trained staff. Cocoa is a non denominational UK registered charity founded in 1995.

Compassion Africa is a family run charity, supporting orphaned children in Sierra Leone, West Africa, developing the Compassion Africa Children’s Village. At Compassion Africa, we want to give children a life of love and hope. Our Children’s Village will put orphaned children back into a family environment.

Compassion UK is an evangelical Christian child development ministry dedicated to addressing the needs of children living in poverty around the world. Compassion's sponsorship programmes are Christ centred, child focused and church based.

COCO is a children's charity that is trying to make a BIG difference to the lives of children affected by poverty, war, famine and disease. COCO wants to give them a positive and happier future

The Constant Gardener Trust, set up to support the communities in Kenya where the majority of the feature film, The Constant Gardener, was filmed, aims to improve the living conditions, educational prospects and health awareness of these communities by enabling both individuals and the communities to become self sufficient and independent through carefully researched, sustainable projects.

Helping Rwanda The Trust works in a remote part of Rwanda to provide clean water, education, and family planning. The Trust is able to respond to local needs as Deri Rundle is on site for 3 months of the year. All the running costs are met by the Trust so that all the funds raised go straight to Rwanda.

Devon Development Education aims to raise awareness of global issues with schools and the community in this country. In Uganda, DDE works with schools to train children in sustainable agriculture and to improve school buildings. DDE has 3 projects to which you can donate funds. These are: The New Build Uganda, Food For Thought School Linking Programme and The Global Centre. To find out more about these projects and to donate specifically to one of them, please go to the following link www.globalcentredevon.org.uk/justgiving

Our first project aims to provide a sustainable water source for a community of 5000 in Kenya. The community is facing severe water shortages and rely on dirty water in the rainy season and have to walk 20 km a day to collect water.

The Edith's Home Project was founded in response to a need we identified whilst working in the community of Ngora, a small town in the Teso region of Uganda. We provide psychological and spiritual support, sponsorship of school fees and vocational training for over 200 orphans.

The Esther Benjamins Trust is a children's charity working mainly in Nepal. It aims to give a childhood back to some of the world's most marginalised and forgotten children, including innocent children who once lived in prisons, street children, deaf and disabled children and children who have been trafficked into India and sold into bonded labour as circus performers.

EveryChild is an international development charity that works with the most vulnerable and marginalised children in many of the world's poorest countries to enable them to grow up free from disease, poverty and exploitation as valued individuals within strong communities.

Established in 2002 Faith & Football is a Christian Charity that seeks to serve the young people and families of our inner cities and to partner with projects overseas that work within poverty stricken areas. We use football as a means of building relationships within local communities to impart life skills and provide the benefits of much needed role models for young people.

families for Children, Zambia work with communities in Zambia, to protect, care for and educate vulnerable children who are affected by HIV/AIDS. Most of the children are orphans and live in abject poverty. They and their families are offered help with food and other basic necessities and supported through school, towards independence.

Feed The Children focuses on the needs of impoverished children and their families across Africa, Asia, Eastern Europe, South America and elsewhere. There are two main aims; to provide emergency aid in the event of disasters, and to support long-term projects that build for sustainable community growth.

Feet First was founded in 2003 by Blackpool Victoria Hospital Consultant Orthopaedic Surgeon Steve Mannion. It's aims are to treat clubfoot in the developing world. It currently focuses its resources on two countries Malawi in Central Africa, and Laos in South East Asia. Please see the website for more information!

It helps the families and child victims of the Chernobyl disaster of 1986 in Ukraine. It personally takes out humanitarian aid 3 times a year in its 3 Transit vans. It also helps deprived children in the UK particularly via HMP. and single parent families at Christmas.

Foosteps is a Christian Charity which focuses on caring for children in need, supporting education and training and fighting poverty and disability. It works with trusted partners in Kenya to provide the Tumaini orphanage, Sunshine home for street boys, wheelchairs, technical skills training, school fees and feeding programmes.

Created in 1996, For A Child's Smile aims to rescue, care for and educate the poorest of Cambodia's children, especially the ones who are forced to scavenge through Phnom Penh's rubbish dumps to survive. FCS focuses on these children's healthcare and social well being and also looks to provide them with an education and vocational training so that they are able to secure a brighter future.

Forever Angels Baby Home provides interim care for abandoned, orphaned and HIV positive children who have no one else to care for them. The Home provides up to 20 children with a loving, stimulating environment caring for their mental, physical, social, emotional and health needs until a more permanent family can be found for them.

FRANK Water Projects funds sustainable projects that provide safe, clean drinking water by installing ultra violet and reverse osmosis water filtering technology which is built into a community owned and run facility. FRANK has funded the installation of over 10 projects in Andhra Pradesh, India benefiting over 100,000 people. Many more projects are currently under development, please visit our website www.frankwaterprojects.org for more information. Charity Registration No 1121273

The Freeplay Foundation is unlike any other non-profit humanitarian organisation in the world. Its mission is to enable access to information and education to the most vulnerable populations through appropriate and sustainable technologies particularly self-powered radios. The Freeplay Foundation is com